Because they work enzymatically, antibiotic resistance is not a factor. Zymox products are antifungal, anti-yeast and partially antibacterial, Brown said.
The otic products are based on an antimicrobial enzyme system containing lactoperoxidase, lactoferrin and lysozyme, explained Deborah Brown, advertising and marketing vice president. in Westmont, Ill., is a treatment program favored by some veterinarians. Zymox, a non-prescription, enzyme-based family of products manufactured by Pet King Brands Inc. Alternatively, he offers clients the choice of bringing in the animal daily to have the ears medicated. A combination of gentamicin 0.3 percent, ketoconazole 2.0 percent and triamcinolone 0.1 percent is favored by Bloom, owner of the Allergy, Skin and Ear Clinic for Pets in Livonia, Mich. ABVP, also uses a compounded product to pack ears weekly in problem patients until the infection resolves. In situations when pet owners are unable to medicate ears topically, I’ve had some success using compounded lanolin-based ear medications that provide a repository effect.” "If one tries this approach, it is important to thoroughly clean the ear canal. "I have rarely found that systemic antimicrobials alone are sufficient to resolve a severe otitis externa case, which typically has copious amounts of organic material in the canal,” said Jon Plant, DVM, owner of the SkinVet Clinic in Lake Oswego, Ore. They also concur that some animals won’t hold still for clients to topically medicate their ears. Experts concur that systemic antibiotics are inadequate to squash the bad-boy bugs of otitis externa.
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